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KMID : 1007320090150010035
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Journal of the Korean Society of Menopause
2009 Volume.15 No. 1 p.35 ~ p.40
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Bone Mineral Density in Patients with Endometrial Cancer
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Lee Seung-Ho
Ku Chun-Hoe
Shin Jin-Woo
Park Jong-Min
Park Chan-Yong
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Abstract
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Objectives: A variety of neoplasms are related to osteoporosis in the absence of metastasis. We sought to evaluate bone mineral density (BMD) in patients with endometrial cancer.
Methods: We retrospectively analyzed the BMD of the spine and femur using dual-energy X-ray absorptiometry (DEXA) in 31 patients with endometrial cancer and 61 control women. The control group was treated with surgery for benign disease. All patients with endometrial cancer and all control women had experienced menopause. There were no bone metastases in patients with endometrial cancer. We compared age, height, body weight, body mass index (BMI), and BMD of the spine and femur between the endometrial cancer and control groups, and compared BMD between stage I and stage II, III, and IV endometrial cancer patients.
Results: There were no differences in the BMD of the spine or femur in patients with endometrial cancer and those in the control group. There were also no differences in the BMD of the spine or femur in patients with stage I versus stage II, III, or IV endometrial cancer.
Conclusion: Endometrial cancer appeared to have no effects on BMD before treatment. However, to define its detailed effect on BMD, a prospective study with large sample size is needed.
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KEYWORD
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Endometrial cancer, Bone mineral density
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